radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma and also in the treatment of graves’ disease. the basis of which is the accumulation of radioactive iodine by the sodium-iodide symporter (nis) in the thyroid gland. expression of nis by extrathyroidal tissues including islets of pancreas has been reported. radioactive iodine uptake ...

the present nuclear leakage crisis from japan is a topic to be discussed in present public health. in radiology, the leaked radioactive elements are considered hazard. here, the author briefly reviews and discusses on two important radio-hazard elements in post nuclear power plant crisis, radioactive iodine and radioactive cesium. based on previous similar nuclear crisis in russia, it is eviden...

introduction: high-dose radioactive iodine therapy in differentiated thyroid cancer (dtc) may adversely affect the salivary gland function. this study is aimed to evaluate the effect of radioactive iodine (rai) with dose of 100 mci in dtc patients compared to lower doses of less than 30 mci in hyperthyroid cases. methods: fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

Radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma (PTC) and in the treatment of Graves' disease (GD). The basis of this therapy is the accumulation of radioactive iodine by the sodium-iodide symporter (NIS) in the thyroid gland. Expression of NIS by extrathyroidal tissues such as islets of pancreas has been reported. Radioactive iod...

introduction: hyperthyroidism is a relatively common disorder caused by different etiologies. graves’ disease, and toxic-nodular goiter (plummer’s disease) are among the most common causes. treatment with radioiodine is considered to be the treatment of choice in many of the patients. higher biological half-life of ¹³¹i in hyperthyroid patients as compared with patients with differentiated thyr...

Introduction: Earlier studies suggest increased serum levels of thyroid peroxidase antibodies (TPOAb) in some cases with non-autoimmune hyperthyroidism. The aim of the study was to assess the incidence of hypothyroidism in patients with nodular toxic goitre and toxic adenoma at 12 months after radioactive iodine therapy in the relation to TPOAb levels. Patients & Measurements: The study compris...

CONTEXT Substantial uncertainty persists about the indications for radioactive iodine for thyroid cancer. Use of radioactive iodine over time and the correlates of its use remain unknown. OBJECTIVE To determine practice patterns, the degree to which hospitals vary in their use of radioactive iodine, and factors that contribute to this variation. DESIGN, SETTING, AND PATIENTS Time trend anal...

BACKGROUND Ablative radioiodine-131 ((131)I) therapy is used in the standart treatment procedure of thyroid carcinoma and procedures using (131)I represent the majority of Nuclear Medicine therapeutic procedures. The principal route of (131)I excretion after the administration of (131)I is the urine. Amifostine is an organic thiophosphate ester prodrug and the kidney concentrations of the activ...

The use of radioactive iodine as an indicator in thyroid physiology has been described by Hertz, Roberts and Evans (1) and by Hertz, Roberts, Means and Evans (2, 3). Hamilton and Soley (4) have published data obtained by the use of radioactive iodine on goiter patients of several types. We have administered radioactive iodine (mainly the 8-day isotope I's1), obtained by bombarding tellurium wit...